Camptocormia in Japanese patients with Parkinson's disease: A multicenter study
Identifieur interne : 000378 ( Main/Exploration ); précédent : 000377; suivant : 000379Camptocormia in Japanese patients with Parkinson's disease: A multicenter study
Auteurs : Morinobu Seki [Japon] ; Kazushi Takahashi [Japon] ; Atsuo Koto [Japon] ; Ban Mihara [Japon] ; Yoko Morita [Japon] ; Kazuo Isozumi [Japon] ; Kouichi Ohta [Japon] ; Kazuhiro Muramatsu [Japon] ; Jun Gotoh [Japon] ; Keiji Yamaguchi [Japon] ; Yutaka Tomita [Japon] ; Hideki Sato [Japon] ; Yoshihiro Nihei [Japon] ; Satoko Iwasawa [Japon] ; Norihiro Suzuki [Japon]Source :
- Movement Disorders [ 0885-3185 ] ; 2011-12.
English descriptors
Abstract
Objective:: The aim of this work was to investigate the prevalence of camptocormia and the clinical characteristics of patients with camptocormia in a large population of PD patients. Background:: Although camptocormia has been recognized as a prominent phenomenon in PD, the previous epidemiological reports were limited, especially in terms of sample size. Methods:: We evaluated 531 PD patients (disease duration: 7.0 ± 5.5 years, mean ± standard deviation). We examined their clinical features and the prevalence of camptocormia. Results:: Camptocormia was detected in 22 patients (4.1%) and found in patients who were older and had more severe motor symptoms and a higher levodopa (L‐dopa) dose (P < 0.05), compared to the patients without camptocormia. Patients with camptocormia showed significantly higher frequencies of autonomic symptoms, such as constipation and urinary incontinence (P < 0.05). Conclusions:: Camptocormia is uncommon in PD and is associated with disease severity, higher L‐dopa dose and higher frequencies of autonomic symptoms. © 2011 Movement Disorder Society
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DOI: 10.1002/mds.23955
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last="Isozumi">Kazuo Isozumi</name><affiliation wicri:level="1"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Neurology, Ashikaga Red Cross Hospital, Tochigi</wicri:regionArea><wicri:noRegion>Tochigi</wicri:noRegion></affiliation></author><author><name sortKey="Ohta, Kouichi" sort="Ohta, Kouichi" uniqKey="Ohta K" first="Kouichi" last="Ohta">Kouichi Ohta</name><affiliation wicri:level="3"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Neurology, Tachikawa Hospital, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Muramatsu, Kazuhiro" sort="Muramatsu, Kazuhiro" uniqKey="Muramatsu K" first="Kazuhiro" last="Muramatsu">Kazuhiro Muramatsu</name><affiliation wicri:level="1"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Neurology, Saiseikai Yokohama‐city Eastern Hospital, 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first="Satoko" last="Iwasawa">Satoko Iwasawa</name><affiliation wicri:level="3"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Preventive Medicine and Public Health, Keio University School of Medicine, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Suzuki, Norihiro" sort="Suzuki, Norihiro" uniqKey="Suzuki N" first="Norihiro" last="Suzuki">Norihiro Suzuki</name><affiliation wicri:level="3"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Neurology, Keio University School of Medicine, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2011-12">2011-12</date><biblScope unit="volume">26</biblScope><biblScope unit="issue">14</biblScope><biblScope unit="page" from="2567">2567</biblScope><biblScope unit="page" to="2571">2571</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">7E17B32D501E15691790BEE21CB17C8975925221</idno><idno type="DOI">10.1002/mds.23955</idno><idno type="ArticleID">MDS23955</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Japanese patients</term><term>Parkinson's disease</term><term>bent spine</term><term>camptocormia</term><term>nonmotor symptom</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Objective:: The aim of this work was to investigate the prevalence of camptocormia and the clinical characteristics of patients with camptocormia in a large population of PD patients. Background:: Although camptocormia has been recognized as a prominent phenomenon in PD, the previous epidemiological reports were limited, especially in terms of sample size. Methods:: We evaluated 531 PD patients (disease duration: 7.0 ± 5.5 years, mean ± standard deviation). We examined their clinical features and the prevalence of camptocormia. Results:: Camptocormia was detected in 22 patients (4.1%) and found in patients who were older and had more severe motor symptoms and a higher levodopa (L‐dopa) dose (P < 0.05), compared to the patients without camptocormia. Patients with camptocormia showed significantly higher frequencies of autonomic symptoms, such as constipation and urinary incontinence (P < 0.05). Conclusions:: Camptocormia is uncommon in PD and is associated with disease severity, higher L‐dopa dose and higher frequencies of autonomic symptoms. © 2011 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Japon</li></country><settlement><li>Tokyo</li></settlement></list><tree><country name="Japon"><noRegion><name sortKey="Seki, Morinobu" sort="Seki, Morinobu" uniqKey="Seki M" first="Morinobu" last="Seki">Morinobu Seki</name></noRegion><name sortKey="Gotoh, Jun" sort="Gotoh, Jun" uniqKey="Gotoh J" first="Jun" last="Gotoh">Jun Gotoh</name><name sortKey="Isozumi, Kazuo" sort="Isozumi, Kazuo" uniqKey="Isozumi K" first="Kazuo" last="Isozumi">Kazuo Isozumi</name><name sortKey="Iwasawa, Satoko" sort="Iwasawa, Satoko" uniqKey="Iwasawa S" first="Satoko" last="Iwasawa">Satoko Iwasawa</name><name sortKey="Koto, Atsuo" sort="Koto, Atsuo" uniqKey="Koto A" first="Atsuo" last="Koto">Atsuo Koto</name><name sortKey="Mihara, Ban" sort="Mihara, Ban" uniqKey="Mihara B" first="Ban" last="Mihara">Ban Mihara</name><name sortKey="Morita, Yoko" sort="Morita, Yoko" uniqKey="Morita Y" first="Yoko" last="Morita">Yoko Morita</name><name sortKey="Muramatsu, Kazuhiro" sort="Muramatsu, Kazuhiro" uniqKey="Muramatsu K" first="Kazuhiro" last="Muramatsu">Kazuhiro Muramatsu</name><name sortKey="Nihei, Yoshihiro" sort="Nihei, Yoshihiro" uniqKey="Nihei Y" first="Yoshihiro" last="Nihei">Yoshihiro Nihei</name><name sortKey="Ohta, Kouichi" sort="Ohta, Kouichi" uniqKey="Ohta K" first="Kouichi" last="Ohta">Kouichi Ohta</name><name sortKey="Sato, Hideki" sort="Sato, Hideki" uniqKey="Sato H" first="Hideki" last="Sato">Hideki Sato</name><name sortKey="Suzuki, Norihiro" sort="Suzuki, Norihiro" uniqKey="Suzuki N" first="Norihiro" last="Suzuki">Norihiro Suzuki</name><name sortKey="Takahashi, Kazushi" sort="Takahashi, Kazushi" uniqKey="Takahashi K" first="Kazushi" last="Takahashi">Kazushi Takahashi</name><name sortKey="Tomita, Yutaka" sort="Tomita, Yutaka" uniqKey="Tomita Y" first="Yutaka" last="Tomita">Yutaka Tomita</name><name sortKey="Yamaguchi, Keiji" sort="Yamaguchi, Keiji" uniqKey="Yamaguchi K" first="Keiji" last="Yamaguchi">Keiji Yamaguchi</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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